User: Guest  Login
Document type:
journal article 
Author(s):
Zhong, JL; Poghosyan, Z; Pennington, CJ; Scott, X; Handsley, MM; Warn, A; Gavrilovic, J; Honert, K; Krüger, A; Span, PN; Sweep, FC; Edwards, DR 
Title:
Distinct functions of natural ADAM-15 cytoplasmic domain variants in human mammary carcinoma. 
Abstract:
Adamalysins [a disintegrin and metalloproteinase (ADAM)] are a family of cell surface transmembrane proteins that have broad biological functions encompassing proteolysis, adhesion, and cell signal regulation. We previously showed that the cytoplasmic domain of ADAM-15 interacts with Src family protein tyrosine kinases and the adaptor protein growth factor receptor binding protein 2 (Grb2). In the present study, we have cloned and characterized four alternatively spliced forms of ADAM-15, which...    »
 
Journal title abbreviation:
Mol Cancer Res 
Year:
2008 
Journal volume:
Journal issue:
Pages contribution:
383-94 
Language:
eng 
Print-ISSN:
1541-7786 
TUM Institution:
r experimentelle Onkologie und Therapieforschung 
Format:
Text