Benutzer: Gast  Login
Dokumenttyp:
journal article 
Autor(en):
Agnelli, G; Haas, S; Ginsberg, JS; Krueger, KA; Dmitrienko, A; Brandt, JT 
Titel:
A phase II study of the oral factor Xa inhibitor LY517717 for the prevention of venous thromboembolism after hip or knee replacement. 
Abstract:
BACKGROUND: LY517717 is an oral direct inhibitor of activated factor X that is currently under clinical development. OBJECTIVES: The aims of this proof-of-concept study in patients undergoing total knee replacement (TKR) or total hip replacement (THR) were to determine whether LY517717 can safely reduce the risk of venous thromboembolism (VTE) and to identify at least one dose of LY517717 that is non-inferior to enoxaparin. METHODS: In a double-blind, parallel-arm, dose-ranging study, patients u...    »
 
Zeitschriftentitel:
J Thromb Haemost 
Jahr:
2007 
Band / Volume:
Heft / Issue:
Seitenangaben Beitrag:
746-53 
Sprache:
eng 
Print-ISSN:
1538-7933 
TUM Einrichtung:
r experimentelle Onkologie und Therapieforschung