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Dokumenttyp:
journal article 
Autor(en):
Boulesteix, AL; Strobl, C; Weidinger, S; Wichmann, HE; Wagenpfeil, S 
Titel:
Multiple testing for SNP-SNP interactions. 
Abstract:
Most genetic diseases are complex, i.e. associated to combinations of SNPs rather than individual SNPs. In the last few years, this topic has often been addressed in terms of SNP-SNP interaction patterns given as expressions linked by logical operators. Methods for multiple testing in high-dimensional settings can be applied when many SNPs are considered simultaneously. However, another less well-known multiple testing problem arises within a fixed subset of SNPs when the logic expression is cho...    »
 
Zeitschriftentitel:
Stat Appl Genet Mol Biol 
Jahr:
2007 
Band / Volume:
Seitenangaben Beitrag:
Article37 
Sprache:
eng 
TUM Einrichtung:
r Dermatologie und Allergologie; r Medizinische Statistik und Epidemiologie