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Document type:
journal article 
Author(s):
Kayed, H; Bekasi, S; Keleg, S; Michalski, CW; Giese, T; Friess, H; Kleeff, J 
Title:
BGLAP is expressed in pancreatic cancer cells and increases their growth and invasion. 
Abstract:
BACKGROUND: Bone gamma-carboxyglutamate protein (BGLAP; osteocalcin) is a small, highly conserved molecule first identified in the mineralized matrix of bone. It has been implicated in the pathophysiology of various malignancies. In this study, we analyzed the expression and role of BGLAP in the normal human pancreas, chronic pancreatitis (CP), and pancreatic ductal adenocarcinoma (PDAC) using quantitative RT-PCR, immunohistochemistry, immunocytochemistry and enzyme immunoassays, as well as cel...    »
 
Journal title abbreviation:
Mol Cancer 
Year:
2007 
Journal volume:
Pages contribution:
83 
Language:
eng 
TUM Institution:
Chirurgiesche Klinik und Poliklinik