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Document type:
journal article 
Author(s):
Novotny, AR; Emmanuel, K; Maier, S; Westerholt, A; Weighardt, H; Stadler, J; Bartels, H; Schwaiger, M; Siewert, JR; Holzmann, B; Heidecke, CD 
Title:
Cytochrome P450 activity mirrors nitric oxide levels in postoperative sepsis: predictive indicators of lethal outcome. 
Abstract:
BACKGROUND: The development of liver failure significantly influences prognosis during the course of major septic complications. Although the underlying cause for septic liver failure is still unclear, research using animal models has demonstrated that an increased nitric oxide (NO) synthesis compromises detoxification processes in the liver. METHODS: In the present study, serum NO levels were measured by high-performance liquid chromatography (HPLC) and aminopyrine breath test (ABT) scores, ref...    »
 
Journal title abbreviation:
Surgery 
Year:
2007 
Journal volume:
141 
Journal issue:
Pages contribution:
376-84 
Language:
eng 
Print-ISSN:
0039-6060 
TUM Institution:
Chirurgiesche Klinik und Poliklinik; Nuklearmedizinische Klinik und Poliklinik