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Document type:
journal article 
Author(s):
Leucht, S; Davis, JM; Engel, RR; Kane, JM; Wagenpfeil, S 
Title:
Defining'response' in antipsychotic drug trials: recommendations for the use of scale-derived cutoffs. 
Abstract:
Scale-derived cutoff points are frequently used to define'response' in antipsychotic drug trials. This procedure is useful, because responder rates can be understood more intuitively than a difference in means of rating scales. As various definitions of response have been used, we examined original participant data to assess whether the choice of the Brief Psychiatric Rating Scale-based response cutoff had an impact on the results of seven (n=1870) antipsychotic drug trials in schizophrenia. We...    »
 
Journal title abbreviation:
Neuropsychopharmacology 
Year:
2007 
Journal volume:
32 
Journal issue:
Pages contribution:
1903-10 
Language:
eng 
Print-ISSN:
0893-133X 
TUM Institution:
Klinik und Poliklinik für Psychiatrie und Psychotherapie ; Institut für Medizinische Statistik und Epidemiologie