Hollow fiber membranes, HFM, have not been established in milk protein fractionation by microfiltration. HFM of different lengths (0.3–1.2 m) were produced to vary the pressure drop along the module and thus to study the length dependent spatial distribution of flux and whey protein transmission along the flow path as a function of transmembrane pressure, ΔpTM, and feed volume flow rate. The objective was to identify the maximally possible module length for various combinations of ΔpTM and flow velocity leading to a pressure close to zero at the module outlet, thus avoiding negative ΔpTM and reverse permeate flow at the module end. A mean ΔpTM of 0.5 bar was identified as optimal for all module lengths to avoid deposit formation above the membrane-controlled limit, reaching a flux of 61.5 L m−2 h−1. An optimal HFM length of 0.6 m was identified for milk protein fractionation to obtain the highest flux and whey protein transmission. The shorter the module system, the higher is the possible volume flow rate to prevent excessive deposit formation and thus to achieve the best possible fractionation result.     «

Hollow fiber membranes, HFM, have not been established in milk protein fractionation by microfiltration. HFM of different lengths (0.3–1.2 m) were produced to vary the pressure drop along the module and thus to study the length dependent spatial distribution of flux and whey protein transmission along the flow path as a function of transmembrane pressure, ΔpTM, and feed volume flow rate. The objective was to identify the maximally possible module length for various combinations of ΔpTM and flow...     »