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Document type:
journal article 
Author(s):
Shinde, Prashant V; Xu, Haifeng C; Maney, Sathish Kumar; Kloetgen, Andreas; Namineni, Sukumar; Zhuang, Yuan; Honke, Nadine; Shaabani, Namir; Bellora, Nicolas; Doerrenberg, Mareike; Trilling, Mirko; Pozdeev, Vitaly I; van Rooijen, Nico; Scheu, Stefanie; Pfeffer, Klaus; Crocker, Paul R; Tanaka, Masato; Duggimpudi, Sujitha; Knolle, Percy; Heikenwalder, Mathias; Ruland, Jürgen; Mak, Tak W; Brenner, Dirk; Pandyra, Aleksandra A; Hoell, Jessica I; Borkhardt, Arndt; Häussinger, Dieter; Lang, Karl S; Lan...    »
 
Title:
Tumor Necrosis Factor-Mediated Survival of CD169 Cells Promotes Immune Activation during Vesicular Stomatitis Virus Infection. 
Abstract:
Innate immune activation is essential to mount an effective antiviral response and to prime adaptive immunity. Although a crucial role of CD169 cells during vesicular stomatitis virus (VSV) infections is increasingly recognized, factors regulating CD169 cells during viral infections remain unclear. Here, we show that tumor necrosis factor is produced by CD11b Ly6C Ly6G cells following infection with VSV. The absence of TNF or TNF receptor 1 (TNFR1) resulted in reduced numbers of CD169 cells and...    »
 
Journal title abbreviation:
J Virol 
Year:
2018 
Journal volume:
92 
Journal issue:
Language:
eng 
Print-ISSN:
0022-538X 
TUM Institution:
Institut für Klinische Chemie und Pathobiochemie