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Dokumenttyp:
Article; Journal Article 
Autor(en):
Poltorak, Mateusz P; Graef, Patricia; Tschulik, Claudia; Wagner, Michaela; Cletiu, Vlad; Dreher, Stefan; Borjan, Bojana; Fraessle, Simon P; Effenberger, Manuel; Turk, Martin; Busch, Dirk H; Plitzko, Juergen; Kugler, David G; Ragan, Seamus; Schmidt, Thomas; Stemberger, Christian; Germeroth, Lothar 
Titel:
Expamers: a new technology to control T cell activation. 
Abstract:
T cell activation is a cornerstone in manufacturing of T cell-based therapies, and precise control over T cell activation is important in the development of the next generation T-cell based therapeutics. This need cannot be fulfilled by currently available methods for T cell stimulation, in particular not in a time dependent manner. Here, we describe a modular activation reagent called Expamers, which addresses these limitations. Expamers are versatile stimuli that are intended for research and...    »
 
Zeitschriftentitel:
Sci Rep 
Jahr:
2020 
Band / Volume:
10 
Heft / Issue:
Print-ISSN:
2045-2322 
TUM Einrichtung:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene