User: Guest  Login
Document type:
Article; Journal Article; Research Support, Non-U.S. Gov't 
Author(s):
Masuda, Takahiro; Amann, Lukas; Sankowski, Roman; Staszewski, Ori; Lenz, Maximilian; D Errico, Paolo; Snaidero, Nicolas; Costa Jordão, Marta Joana; Böttcher, Chotima; Kierdorf, Katrin; Jung, Steffen; Priller, Josef; Misgeld, Thomas; Vlachos, Andreas; Meyer-Luehmann, Melanie; Knobeloch, Klaus-Peter; Prinz, Marco 
Title:
Novel Hexb-based tools for studying microglia in the CNS. 
Abstract:
Microglia and central nervous system (CNS)-associated macrophages (CAMs), such as perivascular and meningeal macrophages, are implicated in virtually all diseases of the CNS. However, little is known about their cell-type-specific roles in the absence of suitable tools that would allow for functional discrimination between the ontogenetically closely related microglia and CAMs. To develop a new microglia gene targeting model, we first applied massively parallel single-cell analyses to compare mi...    »
 
Journal title abbreviation:
Nat Immunol 
Year:
2020 
Journal volume:
21 
Journal issue:
Pages contribution:
802-815 
Print-ISSN:
1529-2908 
TUM Institution:
Lehrstuhl für Zellbiologie des Nervensystems (Prof. Misgeld)