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Document type:
Article; Journal Article; Research Support, Non-U.S. Gov't 
Author(s):
Marisca, Roberta; Hoche, Tobias; Agirre, Eneritz; Hoodless, Laura Jane; Barkey, Wenke; Auer, Franziska; Castelo-Branco, Gonçalo; Czopka, Tim 
Title:
Functionally distinct subgroups of oligodendrocyte precursor cells integrate neural activity and execute myelin formation. 
Abstract:
Recent reports have revealed that oligodendrocyte precursor cells (OPCs) are heterogeneous. It remains unclear whether such heterogeneity reflects different subtypes of cells with distinct functions or instead reflects transiently acquired states of cells with the same function. By integrating lineage formation of individual OPC clones, single-cell transcriptomics, calcium imaging and neural activity manipulation, we show that OPCs in the zebrafish spinal cord can be divided into two functionall...    »
 
Journal title abbreviation:
Nat Neurosci 
Year:
2020 
Journal volume:
23 
Journal issue:
Pages contribution:
363-374 
Print-ISSN:
1097-6256 
TUM Institution:
Lehrstuhl für Zellbiologie des Nervensystems (Prof. Misgeld)