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Document type:
Journal Article; Research Support, Non-U.S. Gov't 
Author(s):
Körber, Nina; Behrends, Uta; Protzer, Ulrike; Bauer, Tanja 
Title:
Evaluation of T-activated proteins as recall antigens to monitor Epstein-Barr virus and human cytomegalovirus-specific T cells in a clinical trial setting. 
Abstract:
BACKGROUND: Pools of overlapping synthetic peptides are routinely used for ex vivo monitoring of antigen-specific T-cell responses. However, it is rather unlikely that these peptides match those resulting from naturally processed antigens. T-activated proteins have been described as immunogenic and more natural stimulants, since they have to pass through antigen processing and comprise activation of all clinically relevant effector cell populations. METHODS: We performed comparative analysis of...    »
 
Journal title abbreviation:
J Transl Med 
Year:
2020 
Journal volume:
18 
Journal issue:
Print-ISSN:
1479-5876 
TUM Institution:
Institut für Virologie ; Klinik und Poliklinik für Kinderheilkunde und Jugendmedizin