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Document type:
Journal Article; Research Support, Non-U.S. Gov't 
Author(s):
Špiranec Spes, Katarina; Chen, Wen; Krebes, Lisa; Völker, Katharina; Abeßer, Marco; Eder Negrin, Petra; Cellini, Antonella; Nickel, Alexander; Nikolaev, Viacheslav O; Hofmann, Franz; Schuh, Kai; Schweda, Frank; Kuhn, Michaela 
Title:
Heart-Microcirculation Connection: Effects of ANP (Atrial Natriuretic Peptide) on Pericytes Participate in the Acute and Chronic Regulation of Arterial Blood Pressure. 
Abstract:
Cardiac ANP (atrial natriuretic peptide) moderates arterial blood pressure. The mechanisms mediating its hypotensive effects are complex and involve inhibition of the renin-angiotensin-aldosterone system, increased natriuresis, endothelial permeability, and vasodilatation. The contribution of the direct vasodilating effects of ANP to blood pressure homeostasis is controversial because variable levels of the ANP receptor, GC-A (guanylyl cyclase-A), are expressed among vascular beds. Here, we show...    »
 
Journal title abbreviation:
Hypertension 
Year:
2020 
Journal volume:
76 
Journal issue:
Pages contribution:
1637-1648 
Print-ISSN:
0194-911X 
TUM Institution:
Institut für Pharmakologie und Toxikologie