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Document type:
Journal Article 
Author(s):
Busse, Madleen; Müller, Mark; Kimm, Melanie A; Ferstl, Simone; Allner, Sebastian; Achterhold, Klaus; Herzen, Julia; Pfeiffer, Franz 
Title:
Three-dimensional virtual histology enabled through cytoplasm-specific X-ray stain for microscopic and nanoscopic computed tomography. 
Abstract:
Many histological methods require staining of the cytoplasm, which provides instrumental details for diagnosis. One major limitation is the production of 2D images obtained by destructive preparation of 3D tissue samples. X-ray absorption micro- and nanocomputed tomography (microCT and nanoCT) allows for a nondestructive investigation of a 3D tissue sample, and thus aids to determine regions of interest for further histological examinations. However, application of microCT and nanoCT to biologic...    »
 
Journal title abbreviation:
Proc Natl Acad Sci U S A 
Year:
2018 
Journal volume:
115 
Journal issue:
10 
Pages contribution:
2293-2298 
Fulltext / DOI:
Print-ISSN:
0027-8424 
TUM Institution:
Institut für Diagnostische und Interventionelle Radiologie