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Document type:
Journal Article; Review 
Author(s):
Clemmensen, Christoffer; Finan, Brian; Müller, Timo D; DiMarchi, Richard D; Tschöp, Matthias H; Hofmann, Susanna M 
Title:
Emerging hormonal-based combination pharmacotherapies for the treatment of metabolic diseases. 
Abstract:
Obesity and its comorbidities, such as type 2 diabetes mellitus and cardiovascular disease, constitute growing challenges for public health and economies globally. The available treatment options for these metabolic disorders cannot reverse the disease in most individuals and have not substantially reduced disease prevalence, which underscores the unmet need for more efficacious interventions. Neurobiological resilience to energy homeostatic perturbations, combined with the heterogeneous pathoph...    »
 
Journal title abbreviation:
Nat Rev Endocrinol 
Year:
2019 
Journal volume:
15 
Journal issue:
Pages contribution:
90-104 
Print-ISSN:
1759-5029 
TUM Institution:
Lehrstuhl für Stoffwechselerkrankungen (Prof. Tschöp)