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Dokumenttyp:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review 
Autor(en):
Metzger, J; Luppa, PB; Good, DM; Mischak, H 
Titel:
Adapting mass spectrometry-based platforms for clinical proteomics applications: The capillary electrophoresis coupled mass spectrometry paradigm. 
Abstract:
Single biomarker detection is common in clinical laboratories due to the currently available method spectrum. For various diseases, however, no specific single biomarker could be identified. A strategy to overcome this diagnostic void is to shift from single analyte detection to multiplexed biomarker profiling. Mass spectrometric methods were employed for biomarker discovery in body fluids. The enormous complexity of biofluidic proteome compartments implies upstream fractionation. For this reaso...    »
 
Zeitschriftentitel:
Crit Rev Clin Lab Sci 
Jahr:
2009 
Band / Volume:
46 
Heft / Issue:
Seitenangaben Beitrag:
129-52 
Sprache:
eng 
Print-ISSN:
1040-8363 
TUM Einrichtung:
Institut für Klinische Chemie und Pathobiochemie