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Document type:
Journal Article; Research Support, Non-U.S. Gov't 
Author(s):
Bareyre, Florence M; Garzorz, Natalie; Lang, Claudia; Misgeld, Thomas; Büning, Hildegard; Kerschensteiner, Martin 
Title:
In vivo imaging reveals a phase-specific role of STAT3 during central and peripheral nervous system axon regeneration. 
Abstract:
In the peripheral nervous system (PNS), damaged axons regenerate successfully, whereas axons in the CNS fail to regrow. In neurons of the dorsal root ganglia (DRG), which extend branches to both the PNS and CNS, only a PNS lesion but not a CNS lesion induces axonal growth. How this differential growth response is regulated in vivo is only incompletely understood. Here, we combine in vivo time-lapse fluorescence microscopy with genetic manipulations in mice to reveal how the transcription factor...    »
 
Journal title abbreviation:
Proc Natl Acad Sci U S A 
Year:
2011 
Journal volume:
108 
Journal issue:
15 
Pages contribution:
6282-7 
Language:
eng 
Print-ISSN:
0027-8424 
TUM Institution:
Lehrstuhl für Zellbiologie des Nervensystems (Prof. Misgeld)