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Dokumenttyp:
Journal Article; Review 
Autor(en):
Fuchs, H; Gailus-Durner, V; Adler, T; Aguilar-Pimentel, JA; Becker, L; Calzada-Wack, J; Da Silva-Buttkus, P; Neff, F; Götz, A; Hans, W; Hölter, SM; Horsch, M; Kastenmüller, G; Kemter, E; Lengger, C; Maier, H; Matloka, M; Möller, G; Naton, B; Prehn, C; Puk, O; Racz, I; Rathkolb, B; Römisch-Margl, W; Rozman, J; Wang-Sattler, R; Schrewe, A; Stöger, C; Tost, M; Adamski, J; Aigner, B; Beckers, J; Behrendt, H; Busch, DH; Esposito, I; Graw, J; Illig, T; Ivandic, B; Klingenspor, M; Klopstock, T; Kremmer...    »
 
Titel:
Mouse phenotyping. 
Abstract:
Model organisms like the mouse are important tools to learn more about gene function in man. Within the last 20 years many mutant mouse lines have been generated by different methods such as ENU mutagenesis, constitutive and conditional knock-out approaches, knock-down, introduction of human genes, and knock-in techniques, thus creating models which mimic human conditions. Due to pleiotropic effects, one gene may have different functions in different organ systems or time points during developme...    »
 
Zeitschriftentitel:
Methods 
Jahr:
2011 
Band / Volume:
53 
Heft / Issue:
Seitenangaben Beitrag:
120-35 
Sprache:
eng 
Print-ISSN:
1046-2023 
TUM Einrichtung:
Institut für Allgemeine Pathologie und Pathologische Anatomie; Institut für Medizinische Mikrobiologie, Immunologie und Hygiene; Klinik und Poliklinik für Dermatologie und Allergologie; Molekulare Allergologie (Prof. Schmidt-Weber)