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Document type:
In Vitro; Journal Article; Research Support, Non-U.S. Gov't 
Author(s):
Reckhenrich, AK; Koch, C; Egana, JT; Plank, C 
Title:
The use of non-viral gene vectors for bioactive poly-(D,L-lactide) implant surfaces in bone tissue engineering. 
Abstract:
The application of scaffolds in bone tissue engineering often comes along with side effects such as poor integrity, low regeneration rates of bone tissue with inadequate functionality, and, in case of non-degradable implants, the necessity of a second removal surgery after therapy. In this study, we coated a bioresorbable FDA-approved poly-(?-caprolactone)-scaffold for bone regeneration with a poly-(D,L-lactide) layer containing copolymer-protected gene vectors to locally provide bone morphogene...    »
 
Journal title abbreviation:
Eur Cell Mater 
Year:
2012 
Journal volume:
23 
Pages contribution:
441-8 
Language:
eng 
Print-ISSN:
1473-2262 
TUM Institution:
Institut für Experimentelle Onkologie und Therapieforschung; Lehrstuhl für Plastische Chirurgie und Handchirurgie (Prof. Machens)