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Document type:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review 
Author(s):
Ganguly, Dipyaman; Haak, Stefan; Sisirak, Vanja; Reizis, Boris 
Title:
The role of dendritic cells in autoimmunity. 
Abstract:
Dendritic cells (DCs) initiate and shape both the innate and adaptive immune responses. Accordingly, recent evidence from clinical studies and experimental models implicates DCs in the pathogenesis of most autoimmune diseases. However, fundamental questions remain unanswered concerning the actual roles of DCs in autoimmunity, both in general and, in particular, in specific diseases. In this Review, we discuss the proposed roles of DCs in immunological tolerance, the effect of the gain or loss of...    »
 
Journal title abbreviation:
Nat Rev Immunol 
Year:
2013 
Journal volume:
13 
Journal issue:
Pages contribution:
566-77 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
1474-1733 
TUM Institution:
Molekulare Allergologie (Prof. Schmidt-Weber)