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Document type:
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't; Article 
Author(s):
Tang, Wenbo; Kowgier, Matthew; Loth, Daan W; Soler Artigas, Maria; Joubert, Bonnie R; Hodge, Emily; Gharib, Sina A; Smith, Albert V; Ruczinski, Ingo; Gudnason, Vilmundur; Mathias, Rasika A; Harris, Tamara B; Hansel, Nadia N; Launer, Lenore J; Barnes, Kathleen C; Hansen, Joyanna G; Albrecht, Eva; Aldrich, Melinda C; Allerhand, Michael; Barr, R Graham; Brusselle, Guy G; Couper, David J; Curjuric, Ivan; Davies, Gail; Deary, Ian J; Dupuis, Josée; Fall, Tove; Foy, Millennia; Franceschini, Nora; Gao,...    »
 
Title:
Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function. 
Abstract:
Genome-wide association studies (GWAS) have identified numerous loci influencing cross-sectional lung function, but less is known about genes influencing longitudinal change in lung function.We performed GWAS of the rate of change in forced expiratory volume in the first second (FEV1) in 14 longitudinal, population-based cohort studies comprising 27,249 adults of European ancestry using linear mixed effects model and combined cohort-specific results using fixed effect meta-analysis to identify n...    »
 
Journal title abbreviation:
PLoS ONE 
Year:
2014 
Journal volume:
Journal issue:
Pages contribution:
e100776 
Language:
eng 
Print-ISSN:
1932-6203 
TUM Institution:
Lehrstuhl für Allgemeinmedizin (Prof. Schneider) (keine SAP-Zuordnung!)