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Document type:
Review; Review 
Author(s):
Hemmer, Bernhard; Kerschensteiner, Martin; Korn, Thomas 
Title:
Role of the innate and adaptive immune responses in the course of multiple sclerosis. 
Abstract:
Multiple sclerosis is a chronic disease of the CNS that leads to substantial disability in most patients. The early phase is characterised by relapses and the later phase by progressive disability. Results from immunological, genetic, and histopathological studies and treatment trials have shown that the immune system plays a key part in the disease course. Findings from animal models and immunological studies of patients with multiple sclerosis suggest a change in the involvement of the immune...    »
 
Journal title abbreviation:
Lancet Neurol 
Year:
2015 
Journal volume:
14 
Journal issue:
Pages contribution:
406-419 
Language:
eng 
Print-ISSN:
1474-4422 
TUM Institution:
Molekulare Immunologie (Prof. Knolle); Neurologische Klinik und Poliklinik