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Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article 
Author(s):
Schmalenberg, Michael; Beaudoin, Christopher; Bulst, Ludwig; Steubl, Dominik; Luppa, Peter B 
Title:
Magnetic bead fluorescent immunoassay for the rapid detection of the novel inflammation marker YKL40 at the point-of-care. 
Abstract:
Pneumonia is one of the leading causes of death worldwide.We present a magnetic bead fluorescent sandwich immunoassay that allows rapid serum measurement of the novel inflammation marker YKL40 (CHI3L1) at the point of care (POC) that could aid pneumonia diagnosis. The magnetic beads serve as the solid phase for separation of YKL40 from serum. The readout is performed using a small and robust fluorescence reader,which detects the turnover of a fluorescent substrate. The assay procedure, from samp...    »
 
Journal title abbreviation:
J Immunol Methods 
Year:
2015 
Journal volume:
427 
Pages contribution:
36-41 
Language:
eng 
Print-ISSN:
0022-1759 
TUM Institution:
Fachgebiet Nephrologie (Prof. Heemann); Institut für Klinische Chemie und Pathobiochemie