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Document type:
Journal Article; Research Support, Non-U.S. Gov't; Article 
Author(s):
Ermolayev, Vladimir; Mohajerani, Pouyan; Ale, Angelique; Sarantopoulos, Athanasios; Aichler, Michaela; Kayser, Gian; Walch, Axel; Ntziachristos, Vasilis 
Title:
Early recognition of lung cancer by integrin targeted imaging in K-ras mouse model. 
Abstract:
Non-small cell lung cancer is characterized by slow progression and high heterogeneity of tumors. Integrins play an important role in lung cancer development and metastasis and were suggested as a tumor marker; however their role in anticancer therapy remains controversial. In this work, we demonstrate the potential of integrin-targeted imaging to recognize early lesions in transgenic mouse model of lung cancer based on spontaneous introduction of mutated human gene bearing K-ras mutation. We c...    »
 
Journal title abbreviation:
Int J Cancer 
Year:
2015 
Journal volume:
137 
Journal issue:
Pages contribution:
1107-18 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
0020-7136 
TUM Institution:
Lehrstuhl für Biologische Bildgebung - Zusammenarbeit mit dem Helmholtz-Zentrum München (Prof. Ntziachristos)