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Document type:
Zeitschriftenaufsatz 
Author(s):
Festring, Daniel; Brockhoff, Anne; Meyerhof, Wolfgang; Hofmann, Thomas 
Title:
Stereoselective synthesis of amides sharing the guanosine 5'-monophosphate scaffold and Umami enhancement studies using human sensory and hT1R1/rT1R3 receptor assays 
Abstract:
Recent studies led to the identification of umami-enhancing (S)-N(2)-(1-carboxyethyl)- and (S)-N(2)-(1-alkylamino)carbonylalkyl)guanosine 5'-monophosphates that, together with their sensorially inactive (R)-stereoisomers, were found to be formed upon Maillard-type glycation of guanosine 5'-monophosphate (5'-GMP) with 1,3-dihydroxyacetone or glyceraldehyde, respectively. As the efficiency of this Maillard-type procedure to generate the amidated derivatives is limited by the low solubility and rea...    »
 
Journal title:
Journal of Agricultural and Food Chemistry 
Year:
2011 
Journal volume:
59 
Journal issue:
16 
Pages contribution:
8875--8885 
Fulltext / DOI:
Print-ISSN:
0021-8561