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Document type:
journal article 
Author(s):
Höfling, Corinna; Shehabi, Emira; Kuhn, Peer-Hendrik; Lichtenthaler, Stefan F; Hartlage-Rübsamen, Maike; Roßner, Steffen 
Title:
Cell Type-Specific Human APP Transgene Expression by Hippocampal Interneurons in the Tg2576 Mouse Model of Alzheimer's Disease. 
Abstract:
Amyloid precursor protein (APP) transgenic animal models of Alzheimer's disease have become versatile tools for basic and translational research. However, there is great heterogeneity of histological, biochemical, and functional data between transgenic mouse lines, which might be due to different transgene expression patterns. Here, the expression of human APP (hAPP) by GABAergic hippocampal interneurons immunoreactive for the calcium binding proteins parvalbumin, calbindin, calretinin, and for...    »
 
Journal title abbreviation:
Front Neurosci 
Year:
2019 
Journal volume:
13 
Pages contribution:
137 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
1662-4548 
TUM Institution:
Institut für Allgemeine Pathologie und pathologische Anatomie