Miller, Aaron M.;Bahmanof, Milad;Zehn, Dietmar;Cohen, Ezra E.W.;Schoenberger, Stephen P.
Leveraging TCR Affinity in Adoptive Immunotherapy against Shared Tumor/Self-Antigens
Cancer Immunology Research
2018
7
1
40-49

Page, Nicolas;Klimek, Bogna;De Roo, Mathias;Steinbach, Karin;Soldati, Hadrien;Lemeille, Sylvain;Wagner, Ingrid;Kreutzfeldt, Mario;Di Liberto, Giovanni;Vincenti, Ilena;Lingner, Thomas;Salinas, Gabriela;Brück, Wolfgang;Simons, Mikael;Murr, Rabih;Kaye, Jonathan;Zehn, Dietmar;Pinschewer, Daniel D.;Merkler, Doron
Expression of the DNA-Binding Factor TOX Promotes the Encephalitogenic Potential of Microbe-Induced Autoreactive CD8+ T Cells
Immunity
2019
50
3
763

Martinez-Usatorre, Amaia;Sempere, Lorenzo F.;Carmona, Santiago J.;Carretero-Iglesia, Laura;Monnot, Gwennaëlle;Speiser, Daniel E.;Rufer, Nathalie;Donda, Alena;Zehn, Dietmar;Jandus, Camilla;Romero, Pedro
MicroRNA-155 Expression Is Enhanced by T-cell Receptor Stimulation Strength and Correlates with Improved Tumor Control in Melanoma
Cancer Immunology Research
2019
7
6
1013-1024

Qiu, Jing;Villa, Matteo;Sanin, David E.;Buck, Michael D.;O’Sullivan, David;Ching, Reagan;Matsushita, Mai;Grzes, Katarzyna M.;Winkler, Frances;Chang, Chih-Hao;Curtis, Jonathan D.;Kyle, Ryan L.;Van Teijlingen Bakker, Nikki;Corrado, Mauro;Haessler, Fabian;Alfei, Francesca;Edwards-Hicks, Joy;Maggi, Leonard B., Jr.;Zehn, Dietmar;Egawa, Takeshi;Bengsch, Bertram;Klein Geltink, Ramon I.;Jenuwein, Thomas;Pearce, Edward J.;Pearce, Erika L.
Acetate Promotes T Cell Effector Function during Glucose Restriction
Cell Reports
2019
27
7
2063-2074.e5

Puleston, Daniel J.;Buck, Michael D.;Klein Geltink, Ramon I.;Kyle, Ryan L.;Caputa, George;O’Sullivan, David;Cameron, Alanna M.;Castoldi, Angela;Musa, Yaarub;Kabat, Agnieszka M.;Zhang, Ying;Flachsmann, Lea J.;Field, Cameron S.;Patterson, Annette E.;Scherer, Stefanie;Alfei, Francesca;Baixauli, Francesc;Austin, S. Kyle;Kelly, Beth;Matsushita, Mai;Curtis, Jonathan D.;Grzes, Katarzyna M.;Villa, Matteo;Corrado, Mauro;Sanin, David E.;Qiu, Jing;Pällman, Nora;Paz, Katelyn;Maccari, Maria Elena;Blazar, Bruce R.;Mittler, Gerhard;Buescher, Joerg M.;Zehn, Dietmar;Rospert, Sabine;Pearce, Edward J.;Balabanov, Stefan;Pearce, Erika L.
Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation
Cell Metabolism
2019
30
2
352-363.e8

Alfei, Francesca;Kanev, Kristiyan;Hofmann, Maike;Wu, Ming;Ghoneim, Hazem E.;Roelli, Patrick;Utzschneider, Daniel T.;von Hoesslin, Madlaina;Cullen, Jolie G.;Fan, Yiping;Eisenberg, Vasyl;Wohlleber, Dirk;Steiger, Katja;Merkler, Doron;Delorenzi, Mauro;Knolle, Percy A.;Cohen, Cyrille J.;Thimme, Robert;Youngblood, Benjamin;Zehn, Dietmar
TOX reinforces the phenotype and longevity of exhausted T cells in chronic viral infection
Nature
2019
571
7764
265-269

Schaeuble, Karin;Cannelle, Hélène;Favre, Stéphanie;Huang, Hsin-Ying;Oberle, Susanne G.;Speiser, Daniel E.;Zehn, Dietmar;Luther, Sanjiv A.
Attenuation of chronic antiviral T-cell responses through constitutive COX2-dependent prostanoid synthesis by lymph node fibroblasts
PLOS Biology
2019
17
7
e3000072

Kanev, Kristiyan;Wu, Ming;Drews, Antar;Roelli, Patrick;Wurmser, Christine;von Hösslin, Madlaina;Zehn, Dietmar
Proliferation-competent Tcf1+ CD8 T cells in dysfunctional populations are CD4 T cell help independent
Proceedings of the National Academy of Sciences
2019
116
40
20070-20076

Blank, Christian U.;Haining, W. Nicholas;Held, Werner;Hogan, Patrick G.;Kallies, Axel;Lugli, Enrico;Lynn, Rachel C.;Philip, Mary;Rao, Anjana;Restifo, Nicholas P.;Schietinger, Andrea;Schumacher, Ton N.;Schwartzberg, Pamela L.;Sharpe, Arlene H.;Speiser, Daniel E.;Wherry, E. John;Youngblood, Benjamin A.;Zehn, Dietmar
Defining ‘T cell exhaustion’
Nature Reviews Immunology
2019
19
11
665-674

Kallies, Axel;Zehn, Dietmar;Utzschneider, Daniel T.
Precursor exhausted T cells: key to successful immunotherapy?
Nature Reviews Immunology
2019
20
2
128-136