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Document type:
Zeitschriftenaufsatz 
Author(s):
Thon, M.P., Myerscough, M.R., Gee, M.W. 
Title:
A Spatially Resolved and Quantitative Model of Early Atherosclerosis 
Abstract:
Atherosclerosis is a major burden for all societies and there is a great need for a deeper understanding of involved key inflammatory, immunological and biomechanical processes. A decisive step for the prevention and medical treatment of atherosclerosis is to predict what conditions determine whether early atherosclerotic plaques continue to grow, stagnate or become regressive. The driving biological and mechanobiological mechanisms that determine the stability of plaques are yet not fully under...    »
 
Keywords:
atherosclerosis, parameter estimation, stability analysis, macrophage recruitment, transmural flow, lipoprotein flux 
Journal title:
Bulletin of Mathematical Biology 
Year:
2019 
Journal volume:
81 
Journal issue:
10 
Pages contribution:
4022-4068 
Covered by:
Scopus 
Notes:
This is a pre-print of an article published in the Bulletin of Mathematical Biology. The final authenticated version is available online at: https://doi.org/10.1007/s11538-019-00646-5 
Status:
Verlagsversion / published