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Document type:
Journal Article; Article 
Author(s):
Götz, Anna; Lehti, Maarit; Donelan, Elizabeth; Striese, Cynthia; Cucuruz, Sebastian; Sachs, Stephan; Yi, Chun-Xia; Woods, Stephen C; Wright, Samuel D; Müller, Timo D; Tschöp, Matthias H; Gao, Yuanqing; Hofmann, Susanna M 
Title:
Circulating HDL levels control hypothalamic astrogliosis via apoA-I. 
Abstract:
Meta-inflammation of hypothalamic areas governing energy homeostasis has recently emerged as a process of potential pathophysiological relevance for the development of obesity and its metabolic sequelae. The current model suggests that diet-induced neuronal injury triggers microgliosis and astrocytosis, conditions which ultimately may induce functional impairment of hypothalamic circuits governing feeding behavior, systemic metabolism, and body weight. Epidemiological data indicate that low circ...    »
 
Journal title abbreviation:
J Lipid Res 
Year:
2018 
Journal volume:
59 
Journal issue:
Pages contribution:
1649-1659 
Fulltext / DOI:
Print-ISSN:
0022-2275 
TUM Institution:
Lehrstuhl für Stoffwechselerkrankungen (Prof. Tschöp)