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Document type:
Journal Article; Lecture; Review 
Author(s):
DiMarchi, Richard D; Mayer, John P; Gelfanov, Vasily M; Tschöp, Matthias 
Title:
Max Bergmann award lecture:Macromolecular medicinal chemistry as applied to metabolic diseases. 
Abstract:
This review presents the scope of research presented in an October 2016 lecture pertaining to the award of the 2015 Max Bergmann Medal. The advancement in synthetic and biosynthetic chemistry as applied to the discovery of novel macromolecular drug candidates is reviewed. The evolution of the technology from the design, synthesis, and development of the first biosynthetic peptides through the emergence of peptide-based incretin agonists that function by multiple biological mechanisms is exemplif...    »
 
Journal title abbreviation:
J Pept Sci 
Year:
2018 
Journal volume:
24 
Journal issue:
Fulltext / DOI:
Print-ISSN:
1075-2617 
TUM Institution:
Lehrstuhl für Stoffwechselerkrankungen (Prof. Tschöp)