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Document type:
journal article 
Author(s):
Graetz, Christiane; Gröger, Adriane; Luessi, Felix; Salmen, Anke; Zöller, Daniela; Schultz, Janine; Siller, Nelly; Fleischer, Vinzenz; Bellenberg, Barbara; Berthele, Achim; Biberacher, Viola; Havla, Joachim; Hecker, Michael; Hohlfeld, Reinhard; Infante-Duarte, Carmen; Kirschke, Jan S; Kümpfel, Tania; Linker, Ralf; Paul, Friedemann; Pfeuffer, Steffen; Sämann, Philipp; Toenges, Gerrit; Weber, Frank; Zettl, Uwe K; Jahn-Eimermacher, Antje; Antony, Gisela; Groppa, Sergiu; Wiendl, Heinz; Hemmer, Bernh...    »
 
Title:
Association of smoking but not HLA-DRB1*15:01, APOE or body mass index with brain atrophy in early multiple sclerosis. 
Abstract:
The course of multiple sclerosis (MS) shows substantial inter-individual variability. The underlying determinants of disease severity likely involve genetic and environmental factors.The aim of this study was to assess the impact of APOE and HLA polymorphisms as well as smoking and body mass index (BMI) in the very early MS course.Untreated patients ( n = 263) with a recent diagnosis of relapsing-remitting (RR) MS or clinically isolated syndrome underwent standardized magnetic resonance imaging...    »
 
Journal title abbreviation:
Mult Scler 
Year:
2019 
Journal volume:
25 
Journal issue:
Pages contribution:
661-668 
Language:
eng 
Print-ISSN:
1352-4585 
TUM Institution:
Klinik und Poliklinik für Neurologie