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Document type:
journal article 
Author(s):
Hu, Michael S; Cheng, Justin; Borrelli, Mimi R; Leavitt, Tripp; Walmsley, Graham G; Zielins, Elizabeth R; Hong, Wan Xing; Cheung, Alexander T M; Duscher, Dominik; Maan, Zeshaan N; Irizarry, Dre M; Stephan, Brad; Parsa, Fereydoun Don; Wan, Derrick C; Gurtner, Geoffrey C; Lorenz, Hermann Peter; Longaker, Michael T 
Title:
An Improved Humanized Mouse Model for Excisional Wound Healing Using Double Transgenic Mice. 
Abstract:
Splinting full-thickness cutaneous wounds in mice has allowed for a humanized model of wound healing. Delineating the epithelial edge and assessing time to closure of these healing wounds via macroscopic visualization have remained a challenge. Double transgenic mice were created by crossbreeding K14-Cre and ROSA reporter mice. Full-thickness excisional wounds were created in K14-Cre/ROSA mice ( = 5) and imaged using both normal and fluorescent light on the day of surgery, and every other posto...    »
 
Journal title abbreviation:
Adv Wound Care (New Rochelle) 
Year:
2018 
Journal volume:
Journal issue:
Pages contribution:
11-17 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
2162-1918 
TUM Institution:
Klinik und Poliklinik für Plastische Chirurgie und Handchirurgie