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Document type:
journal article 
Author(s):
Striegel, Lisa; Brandl, Beate; Kopp, Markus; Sam, Lukas; Skurk, Thomas; Rychlik, Michael 
Title:
Quantitation of 5-methyltetraydrofolic acid in plasma for determination of folate status and clinical studies by stable isotope dilution assays. 
Abstract:
Folates play a key role in the prevention of neural tube defects in newborns. Thus, it is important to reliably determine the bioavailability of folates from various foods. Accurate analytical methods are essential for quantifying blood-folates, especially in human studies. Here, we present the development and validation of a sensitive method using stable isotope dilution liquid chromatography coupled with mass spectrometry for determining various folates in plasma. Moreover, this study reports...    »
 
Journal title abbreviation:
PLoS ONE 
Year:
2019 
Journal volume:
14 
Journal issue:
Pages contribution:
e0212255 
Language:
eng 
TUM Institution:
Klinik für Ernährungsmedizin