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Document type:
Zeitschriftenaufsatz 
Author(s):
Zolg, Daniel Paul; Wilhelm, Mathias; Schmidt, Tobias; Médard, Guillaume; Zerweck, Johannes; Knaute, Tobias; Wenschuh, Holger; Reimer, Ulf; Schnatbaum, Karsten; Kuster, Bernhard 
Title:
ProteomeTools: Systematic Characterization of 21 Post-translational Protein Modifications by Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS) Using Synthetic Peptides 
Abstract:
The analysis of the post-translational modification (PTM) state of proteins using mass spectrometry-based bottom-up proteomic workflows has evolved into a powerful tool for the study of cellular regulatory events that are not directly encoded at the genome level. Besides frequently detected modifications such as phosphorylation, acetylation and ubiquitination, many low abundant or less frequently detected PTMs are known or postulated to serve important regulatory functions. To more broadly under...    »
 
Journal title:
Molecular & Cellular Proteomics 
Year:
2018 
Journal volume:
17 
Journal issue:
Pages contribution:
1850-1863 
Publisher:
American Society for Biochemistry & Molecular Biology (ASBMB) 
E-ISSN:
1535-94761535-9484 
Date of publication:
29.05.2018