In the current study, KLK9 and KLK10 expression in tumor tissue of patients afflicted with advanced high-grade serous ovarian (HGSOC) and triple-negative breast cancer (TNBC), respectively, was investigated. Together with available KLK11 and KLK15 data in the identical cohorts, coordinate expression was observed between KLK10/KLK11 (and between KLK9/KLK15). Moreover, while elevated KLK10 levels represent an independent favorable prognostic marker in HGSOC, elevated KLK10 expression was independently related with worse prognosis.
«In the current study, KLK9 and KLK10 expression in tumor tissue of patients afflicted with advanced high-grade serous ovarian (HGSOC) and triple-negative breast cancer (TNBC), respectively, was investigated. Together with available KLK11 and KLK15 data in the identical cohorts, coordinate expression was observed between KLK10/KLK11 (and between KLK9/KLK15). Moreover, while elevated KLK10 levels represent an independent favorable prognostic marker in HGSOC, elevated KLK10 expression was independe...
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