User: Guest  Login
Document type:
journal article 
Author(s):
Jefferies, Benedict; Lenze, Florian; Sathe, Anuja; Truong, Nguyen; Anton, Martina; von Eisenhart-Rothe, Rüdiger; Nawroth, Roman; Mayer-Kuckuk, Philipp 
Title:
Non-invasive imaging of engineered human tumors in the living chicken embryo. 
Abstract:
The growing interest in engineered tumor models prompted us to devise a method for the non-invasive assessment of such models. Here, we report on bioluminescence imaging (BLI) for the assessment of engineered tumor models in the fertilized chicken egg, i.e, chick chorioallantoic membrane (CAM) assay. One prostate cancer (PC-3) and two osteosarcoma (MG63 and HOS) cell lines were modified with luciferase reporter genes. To create engineered tumors, these cell lines were seeded either onto basement...    »
 
Journal title abbreviation:
Sci Rep 
Year:
2017 
Journal volume:
Journal issue:
Pages contribution:
4991 
Language:
eng 
TUM Institution:
Institut für experimentelle Onkologie und Therapieforschung