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Document type:
journal article 
Author(s):
Collado-Alsina, Andrea; Hofmann, Franz; Sánchez-Prieto, José; Torres, Magdalena 
Title:
Altered Synaptic Membrane Retrieval after Strong Stimulation of Cerebellar Granule Neurons in Cyclic GMP-Dependent Protein Kinase II (cGKII) Knockout Mice. 
Abstract:
The nitric oxide (NO)/cyclic guanosine monophosphate (cGMP)/cGMP-dependent protein kinase (cGK) signaling pathway regulates the clustering and the recruitment of proteins and vesicles to the synapse, thereby adjusting the exoendocytic cycle to the intensity of activity. Accordingly, this pathway can accelerate endocytosis following large-scale exocytosis, and pre-synaptic cGK type II (cGKII) plays a major role in this process, controlling the homeostatic balance of vesicle exocytosis and endocyt...    »
 
Journal title abbreviation:
Int J Mol Sci 
Year:
2017 
Journal volume:
18 
Journal issue:
11 
Language:
eng 
TUM Institution:
Institut für Pharmakologie und Toxikologie