User: Guest  Login
Document type:
Zeitschriftenaufsatz 
Author(s):
Steck, Natalie; Mueller, Kerstin; Schemann, Michael; Haller, Dirk 
Title:
Bacterial proteases in {IBD} and {IBS}. 
Abstract:
Proteases play a decisive role in health and disease. They fulfil diverse functions and have been associated with the pathology of gastrointestinal disorders such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). The current knowledge focuses on host-derived proteases including matrix metalloproteinases, various serine proteases and cathepsins. The possible contribution of bacterial proteases has been largely ignored in the pathogenesis of IBD and IBS, although there is in...    »
 
Keywords:
Sensitivity and Specificity, Humans, Female, Male, Bacterial Physiological Phenomena, Disease Susceptibility, Inflammatory Bowel Diseases/*enzymology/*microbiology, Irritable Bowel Syndrome/*enzymology/*microbiology, Peptide Hydrolases/analysis/*metabolism, Risk Assessment 
Journal title:
Gut 
Year:
2012 
Journal volume:
61 
Month:
nov 
Journal issue:
11 
Pages contribution:
1610--1618 
Language:
eng 
Print-ISSN:
1468-3288 0017-5749