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Document type:
journal article 
Author(s):
Marzaioli, Viviana; Groß, Christina J; Weichenmeier, Ingrid; Schmidt-Weber, Carsten B; Gutermuth, Jan; Groß, Olaf; Alessandrini, Francesca 
Title:
Specific Surface Modifications of Silica Nanoparticles Diminish Inflammasome Activation and In Vivo Expression of Selected Inflammatory Genes. 
Abstract:
Silica (SiO?) nanoparticles (NPs) usage includes, but is not limited to, industrial and biomedical applications. Toxic effects of SiO? NPs have been explored either or , assessing different surface modifications to reduce their harmful effects. Here, murine bone marrow-derived dendritic (BMDC) and a mouse model of mild allergic inflammation were used to study inflammasome activation and lung inflammation. Our results showed that SiO? plain NPs induced NACHT, LRR and PYD domains-containing prote...    »
 
Journal title abbreviation:
Nanomaterials (Basel) 
Year:
2017 
Journal volume:
Journal issue:
11 
Language:
eng 
Print-ISSN:
2079-4991 
TUM Institution:
Institut für Molekulare Allergologie