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Document type:
journal article 
Author(s):
Backert, Steffen; Haas, Rainer; Gerhard, Markus; Naumann, Michael 
Title:
The Helicobacter pylori Type IV Secretion System Encoded by the cag Pathogenicity Island: Architecture, Function, and Signaling. 
Abstract:
Various gram-negative pathogens express type IV secretion systems (T4SSs) which translocate bacterial virulence factors into host target cells to hijack cellular processes for their own benefit and causing disease. The pathology of Helicobacter pylori, the causative agent of chronic gastritis, peptic ulcer disease, and gastric cancer in humans, strongly depends on a T4SS encoded by the cag pathogenicity island (cagPAI). This T4SS represents a pilus-like structure and a membrane-spanning complex....    »
 
Journal title abbreviation:
Curr Top Microbiol Immunol 
Year:
2017 
Journal volume:
413 
Pages contribution:
187-220 
Language:
eng 
Print-ISSN:
0070-217X 
TUM Institution:
Institut für Medizinische Mikrobiologie, Immunologie und Hygiene