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Document type:
journal article 
Author(s):
Honrath, Birgit; Matschke, Lina; Meyer, Tammo; Magerhans, Lena; Perocchi, Fabiana; Ganjam, Goutham K; Zischka, Hans; Krasel, Cornelius; Gerding, Albert; Bakker, Barbara M; Bünemann, Moritz; Strack, Stefan; Decher, Niels; Culmsee, Carsten; Dolga, Amalia M 
Title:
SK2 channels regulate mitochondrial respiration and mitochondrial Ca uptake. 
Abstract:
Mitochondrial calcium ([Ca]) overload and changes in mitochondrial metabolism are key players in neuronal death. Small conductance calcium-activated potassium (SK) channels provide protection in different paradigms of neuronal cell death. Recently, SK channels were identified at the inner mitochondrial membrane, however, their particular role in the observed neuroprotection remains unclear. Here, we show a potential neuroprotective mechanism that involves attenuation of [Ca] uptake upon SK chann...    »
 
Journal title abbreviation:
Cell Death Differ 
Year:
2017 
Journal volume:
24 
Journal issue:
Pages contribution:
761-773 
Language:
eng 
Print-ISSN:
1350-9047 
TUM Institution:
Institut für Toxikologie und Umwelthygiene