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Document type:
Journal Article; Article 
Author(s):
Bunk, Eva C; Ertaylan, Gökhan; Ortega, Felipe; Pavlou, Maria A; Gonzalez Cano, Laura; Stergiopoulos, Athanasios; Safaiyan, Shima; Völs, Sandra; van Cann, Marianne; Politis, Panagiotis K; Simons, Mikael; Berninger, Benedikt; Del Sol, Antonio; Schwamborn, Jens C 
Title:
Prox1 Is Required for Oligodendrocyte Cell Identity in Adult Neural Stem Cells of the Subventricular Zone. 
Abstract:
Adult neural stem cells with the ability to generate neurons and glia cells are active throughout life in both the dentate gyrus (DG) and the subventricular zone (SVZ). Differentiation of adult neural stem cells is induced by cell fate determinants like the transcription factor Prox1. Evidence has been provided for a function of Prox1 as an inducer of neuronal differentiation within the DG. We now show that within the SVZ Prox1 induces differentiation into oligodendrocytes. Moreover, we find tha...    »
 
Journal title abbreviation:
Stem Cells 
Year:
2016 
Journal volume:
34 
Journal issue:
Pages contribution:
2115-29 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
1066-5099 
TUM Institution:
Lehrstuhl für Zellbiologie des Nervensystems (Prof. Misgeld)