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Document type:
journal article 
Author(s):
Viereck, Janika; Kumarswamy, Regalla; Foinquinos, Ariana; Xiao, Ke; Avramopoulos, Petros; Kunz, Meik; Dittrich, Marcus; Maetzig, Tobias; Zimmer, Karina; Remke, Janet; Just, Annette; Fendrich, Jasmin; Scherf, Kristian; Bolesani, Emiliano; Schambach, Axel; Weidemann, Frank; Zweigerdt, Robert; de Windt, Leon J; Engelhardt, Stefan; Dandekar, Thomas; Batkai, Sandor; Thum, Thomas 
Title:
Long noncoding RNA Chast promotes cardiac remodeling. 
Abstract:
Recent studies highlighted long noncoding RNAs (lncRNAs) to play an important role in cardiac development. However, understanding of lncRNAs in cardiac diseases is still limited. Global lncRNA expression profiling indicated that several lncRNA transcripts are deregulated during pressure overload-induced cardiac hypertrophy in mice. Using stringent selection criteria, we identified Chast (cardiac hypertrophy-associated transcript) as a potential lncRNA candidate that influences cardiomyocyte hype...    »
 
Journal title abbreviation:
Sci Transl Med 
Year:
2016 
Journal volume:
Journal issue:
326 
Pages contribution:
326ra22 
Language:
eng 
Print-ISSN:
1946-6234 
TUM Institution:
Institut für Pharmakologie und Toxikologie