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Dokumenttyp:
journal article 
Autor(en):
Prajeeth, Chittappen K; Kronisch, Julius; Khorooshi, Reza; Knier, Benjamin; Toft-Hansen, Henrik; Gudi, Viktoria; Floess, Stefan; Huehn, Jochen; Owens, Trevor; Korn, Thomas; Stangel, Martin 
Titel:
Effectors of Th1 and Th17 cells act on astrocytes and augment their neuroinflammatory properties. 
Abstract:
Autoreactive Th1 and Th17 cells are believed to mediate the pathology of multiple sclerosis in the central nervous system (CNS). Their interaction with microglia and astrocytes in the CNS is crucial for the regulation of the neuroinflammation. Previously, we have shown that only Th1 but not Th17 effectors activate microglia. However, it is not clear which cells are targets of Th17 effectors in the CNS.To understand the effects driven by Th17 cells in the CNS, we induced experimental autoimmune e...    »
 
Zeitschriftentitel:
J Neuroinflammation 
Jahr:
2017 
Band / Volume:
14 
Heft / Issue:
Seitenangaben Beitrag:
204 
Sprache:
eng 
TUM Einrichtung:
Neurologische Klinik und Poliklinik; Lehrstuhl für Molekulare Neuroimmunologie