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Dokumenttyp:
journal article 
Autor(en):
Resch, A F; Landry, G; Kamp, F; Cabal, G; Belka, C; Wilkens, J J; Parodi, K; Dedes, G 
Titel:
Quantification of the uncertainties of a biological model and their impact on variable RBE proton treatment plan optimization. 
Abstract:
In proton radiation therapy, a relative biological effectiveness (RBE) equal to 1.1 is currently assumed, although biological experiments show that it is not constant. The purpose of this study was to quantify the uncertainties of a published biological model and explore their impact on variable RBE treatment plan (TP) optimization.Two patient cases with a high and a low (?/?)x tumor were investigated. Firstly, intensity modulated proton therapy TPs assuming constant RBE were derived, and subseq...    »
 
Zeitschriftentitel:
Phys Med 
Jahr:
2017 
Band / Volume:
36 
Seitenangaben Beitrag:
91-102 
Sprache:
eng 
Print-ISSN:
1120-1797 
TUM Einrichtung:
Klinik und Poliklinik für RadioOnkologie und Strahlentherapie