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Document type:
journal article 
Author(s):
Lee, Heekyoung; Qian, Kun; von Toerne, Christine; Hoerburger, Lena; Claussnitzer, Melina; Hoffmann, Christoph; Glunk, Viktoria; Wahl, Simone; Breier, Michaela; Eck, Franziska; Jafari, Leili; Molnos, Sophie; Grallert, Harald; Dahlman, Ingrid; Arner, Peter; Brunner, Cornelia; Hauner, Hans; Hauck, Stefanie M; Laumen, Helmut 
Title:
Allele-specific quantitative proteomics unravels molecular mechanisms modulated by cis-regulatory PPARG locus variation. 
Abstract:
Genome-wide association studies identified numerous disease risk loci. Delineating molecular mechanisms influenced by cis-regulatory variants is essential to understand gene regulation and ultimately disease pathophysiology. Combining bioinformatics and public domain chromatin information with quantitative proteomics supports prediction of cis-regulatory variants and enabled identification of allele-dependent binding of both, transcription factors and coregulators at the type 2 diabetes associat...    »
 
Journal title abbreviation:
Nucleic Acids Res 
Year:
2017 
Journal volume:
45 
Journal issue:
Pages contribution:
3266-3279 
Language:
eng 
Fulltext / DOI:
Print-ISSN:
0305-1048 
TUM Institution:
Klinik für Ernährungsmedizin