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Document type:
journal article 
Author(s):
Klöppel, Günter; La Rosa, Stefano 
Title:
Ki67 labeling index: assessment and prognostic role in gastroenteropancreatic neuroendocrine neoplasms. 
Abstract:
In 1983, a monoclonal antibody, Ki67, was generated, that labeled the nuclei of proliferating non-neoplastic and neoplastic cells. The name Ki67 derived from the city of Kiel (Ki) where the antibody was produced in the university department of pathology and refers to the number of the original clone (67). Systematic assessment of the proliferative activity of tumors using Ki67 started in the 1990s, when Ki67, which only worked on frozen tissue, was complemented by the antibody MIB-1 that also wo...    »
 
Journal title abbreviation:
Virchows Arch 
Year:
2018 
Journal volume:
472 
Journal issue:
Pages contribution:
341-349 
Language:
eng 
Print-ISSN:
0945-6317 
TUM Institution:
Institut für Allgemeine Pathologie und pathologische Anatomie