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Document type:
Zeitschriftenaufsatz 
Author(s):
Winkeljann, Benjamin; Boettcher, Kathrin; Balzer, Bizan N.; Lieleg, Oliver 
Title:
Mucin Coatings Prevent Tissue Damage at the Cornea-Contact Lens Interface 
Abstract:
With a prevalence of more than 10%, keratoconjunctivitis sicca (commonly known as dry eye syndrome) is one of the most frequent forms of ocular diseases; among contact lens wearers, this condition occurs even more often. Key components of the protective tear film are mucins, large glycoproteins that serve as molecular lubricants on many epithelial body surfaces. It is likely that, in the absence of a proper mucinous lubrication layer on the cornea surface, increased friction and tissue damage i...    »
 
Keywords:
cornea; dry eye; lubrication; surface modification; tribology; ATOMIC-FORCE MICROSCOPY; FRICTION COEFFICIENT MEASUREMENT; OCULAR SURFACE; ARTICULAR-CARTILAGE; TAPPING-MODE; TRACT MUCINS; TEAR FILM; WEAR; LUBRICATION; XEROSTOMIA 
Dewey Decimal Classification:
500 Naturwissenschaften 
Journal title:
Advanced Materials Interfaces 
Year:
2017 
Journal volume:
Journal issue:
19 
Pages contribution:
1700186 
Covered by:
Scopus 
Reviewed:
ja 
Language:
en 
Fulltext / DOI:
Publisher:
Wiley-Blackwell 
E-ISSN:
2196-7350 
Date of publication:
25.07.2017 
TUM Institution:
Fachgebiet für Biomechanik, MW 
Format:
Bild/Text