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Dokumenttyp:
journal article 
Autor(en):
Kunzke, Thomas; Balluff, Benjamin; Feuchtinger, Annette; Buck, Achim; Langer, Rupert; Luber, Birgit; Lordick, Florian; Zitzelsberger, Horst; Aichler, Michaela; Walch, Axel 
Titel:
Native glycan fragments detected by MALDI-FT-ICR mass spectrometry imaging impact gastric cancer biology and patient outcome. 
Abstract:
Glycosylation in cancer is a highly dynamic process that has a significant impact on tumor biology. Further, the attachment of aberrant glycan forms is already considered a hallmark of the disease state. Mass spectrometry has become a prominent approach to analyzing glycoconjugates. Specifically, matrix-assisted laser desorption/ionisation -mass spectrometric imaging (MALDI-MSI) is a powerful technique that combines mass spectrometry with histology and enables the spatially resolved and label-fr...    »
 
Zeitschriftentitel:
Oncotarget 
Jahr:
2017 
Band / Volume:
Heft / Issue:
40 
Seitenangaben Beitrag:
68012-68025 
Sprache:
eng 
TUM Einrichtung:
Institut für Allgemeine Pathologie und pathologische Anatomie