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Document type:
journal article 
Author(s):
Hachmöller, Oliver; Aichler, Michaela; Schwamborn, Kristina; Lutz, Lisa; Werner, Martin; Sperling, Michael; Walch, Axel; Karst, Uwe 
Title:
Investigating the influence of standard staining procedures on the copper distribution and concentration in Wilson's disease liver samples by laser ablation-inductively coupled plasma-mass spectrometry. 
Abstract:
The influence of rhodanine and haematoxylin and eosin (HE) staining on the copper distribution and concentration in liver needle biopsy samples originating from patients with Wilson's disease (WD), a rare autosomal recessive inherited disorder of the copper metabolism, is investigated. In contemporary diagnostic of WD, rhodanine staining is used for histopathology, since rhodanine and copper are forming a red to orange-red complex, which can be recognized in the liver tissue using a microscope....    »
 
Journal title abbreviation:
J Trace Elem Med Biol 
Year:
2017 
Journal volume:
44 
Pages contribution:
71-75 
Language:
eng 
Print-ISSN:
0946-672X 
TUM Institution:
Institut für Allgemeine Pathologie und pathologische Anatomie